Paper Title:
Periostal Reconstruction Using New Porcine Microstructured Collagen Membrane and Calcium Phosphate Cement: A Dog Model
  Abstract

The aim of this study was to evaluate the capacity of the association of calcium phosphate cement with collagen membrane for large segmental bone defect. Six adult beagle dog underwent defect creation in the ulna and was reconstructed with combination of macroporous calcium phosphate cement MCPC® and resorbable collagen membrane EZ Cure®. After 6 months of implantation, the samples were analyzed with Micro CT, light microscopy and SEM using BSE. Bridging of the defect with a lamellar and well organized bone was achieved in all animals. MCPC granules resorption was increased at the extremities of the implant. Collagen membrane at the expense of the implant was replaced by periosteum-like formation. The results demonstrate the ability of the composite to reconstruct large segmental and critical size defect in long bone.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
257-260
DOI
10.4028/www.scientific.net/KEM.396-398.257
Citation
F. Jegoux, E. Goyenvalle, E. Aguado, R. Cognet, F. Moreau, G. Daculsi, "Periostal Reconstruction Using New Porcine Microstructured Collagen Membrane and Calcium Phosphate Cement: A Dog Model", Key Engineering Materials, Vols. 396-398, pp. 257-260, 2009
Online since
October 2008
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Price
$32.00
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