Paper Title:
Biocompatibility of Bovine Anorganic Xenograft
  Abstract

Porous granules without organic residues were produced from bovine medular anorganic bone. Sample showed carbonate content and crystalline order similar to natural bone. The cytotoxicity of anorganic bovine xenograft (Ossĕus®) was valuated from fibroblasts (1.5x104/cm2) cultured in serial diluted extract (0 – 100%) of Ossĕus plus 10% of fetal bovine serum (FBS). Pure extract (100%) reduced in 15% the number of viable cells (p<0.05, ANOVA, Tukey test) indicating very low cytotoxicity. Samples were implanted in the subcutaneous tissue of mice in order to evaluate tissue reaction. An organized connective tissue in contact to the granules was observed nine weeks after implantation. The anorganic bovine xenograft (Ossĕus®) was biocompatible and its behavior and osteoconduction potential should be evaluated in bony defects.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
3-6
DOI
10.4028/www.scientific.net/KEM.396-398.3
Citation
C.L. Jardelino, E. R. Takamori, S. R. A. Santos, A. M. Rossi, J. M. Granjeiro, "Biocompatibility of Bovine Anorganic Xenograft", Key Engineering Materials, Vols. 396-398, pp. 3-6, 2009
Online since
October 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: J.W. Choi, Hyung M. Cho, E.K. Kwak, T.G. Kwon, H.M. Ryoo, Young Keun Jeong, Kyung Sik Oh, Hong In Shin
47
Authors: D. Marković, V. Živojinović, V. Koković, V. Jokanović
555
Authors: Xiao Yan Lin, Hong Song Fan, Xu Dong Li, Min Tang, Xing Dong Zhang
553
Authors: Marie Strnadová, Jiri Protivinsky, J. Strnad, Zdenka Vejsicka
Abstract:The low temperature macro and micro porous hydroxyapatite scaffold was synthesized. The synthetic nanostructured HA powder was prepared by...
211
Authors: Deni Noviana, Sri Estuningsih, Devi Paramitha, Mokhammad Fakhrul Ulum, Hendra Hermawan
Chapter 7: Biomaterials and Biomedical Engineering
Abstract:A foreign body is any object originating outside the body. It may migrate from its entry site and cause pain, inflammation and infection....
449