Pre-Clinical Analysis of an Acetabular Cup with Improved In Vivo Stability and Integrity

Browne, M.; Dickinson, Alex; Taylor, Andy; Jeffers, Jonathan

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Paper Titles

Histomorphometric Analysis of Bone Repair in Critical Size Defect in Rats Calvaria Treated with Hydroxyapatite and Zinc-Containing Hydroxyapatite 5%, p.15
In Vitro and In Vivo Behaviour of a Ceramic with Interconnected Macroporosity, p.19
In Vitro Characterization / Degradation of Two Bioglasses Used as Synthetic Alloplasts for Bone Grafting, p.23
In Vitro Characterization of Porous Ceramic Based Calcium Phosphate Processing with Albumin, p.27
Pre-Clinical Analysis of an Acetabular Cup with Improved In Vivo Stability and Integrity, p.31
Surface Analysis and Cell Biology Technique in Understanding Degradation of Natural Temporary Teeth Collected from an Area with High Pollution, p.35
A Collagen Grafting on Hydroxyapatite to Enhancement of Bone Cell Attachment, p.41
Adsorption of Proteins Derived from Fetal Bovine Serum onto Hydroxyapatite Nanocrystals with Quartz Crystal Microbalance Technique, p.47
Biocompatibility Properties of ZrO₂ Ceramics and ZrO₂-TiN Composites , p.51

Home > Key Engineering Materials > Bioceramics 21 > Pre-Clinical Analysis of an Acetabular Cup with...

Paper Title:

Pre-Clinical Analysis of an Acetabular Cup with Improved In Vivo Stability and Integrity

Periodical	Key Engineering Materials (Volumes 396 - 398)
Main Theme	Bioceramics 21
Edited by	Marcelo Prado and Cecília Zavaglia
Pages	31-34
DOI	10.4028/www.scientific.net/KEM.396-398.31
Citation	Alex Dickinson et al., 2008, Key Engineering Materials, 396-398, 31
Online since	October, 2008
Authors	Alex Dickinson, M. Browne, Jonathan Jeffers, Andy Taylor
Keywords	Finite Element Analysis (FEA), Preclinical Analysis, Prosthesis Design
Price	US$ 28,-

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Abstract

In recent years, the processing of porous ceramic materials for implant applications has motivated the development and optimization of new technologies. To this purpose, a globular protein based (i.e. ovalbumin) consolidation approach has been proposed. In the present study, a porous hydroxyapatite:b-tricalcium phosphate - biphasic ceramics (BCP), was processed by consolidation using the protein-action technique. The processed ceramic materials exhibited appropriate pore configuration in terms of size, morphology and distribution. The in vitro reactivity and dissolution behavior of the ceramics was evaluated in SBF and biocompatibility in an osteoblasts culture, respectively. Overall, the materials tested showed biocompatibility and suitable properties for osteoconduction. A rough surface pattern displayed by the ceramics seemed to have improved both; cell adhesion and proliferation processes. In conclusion, this study revealed that the porous matrices obtained, promoted suitable development of cell metabolism without cellular death.