Paper Title:
Pre-Clinical Analysis of an Acetabular Cup with Improved In Vivo Stability and Integrity
  Abstract

In recent years, the processing of porous ceramic materials for implant applications has motivated the development and optimization of new technologies. To this purpose, a globular protein based (i.e. ovalbumin) consolidation approach has been proposed. In the present study, a porous hydroxyapatite:b-tricalcium phosphate - biphasic ceramics (BCP), was processed by consolidation using the protein-action technique. The processed ceramic materials exhibited appropriate pore configuration in terms of size, morphology and distribution. The in vitro reactivity and dissolution behavior of the ceramics was evaluated in SBF and biocompatibility in an osteoblasts culture, respectively. Overall, the materials tested showed biocompatibility and suitable properties for osteoconduction. A rough surface pattern displayed by the ceramics seemed to have improved both; cell adhesion and proliferation processes. In conclusion, this study revealed that the porous matrices obtained, promoted suitable development of cell metabolism without cellular death.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
31-34
DOI
10.4028/www.scientific.net/KEM.396-398.31
Citation
A. Dickinson, M. Browne, J. Jeffers, A. Taylor, "Pre-Clinical Analysis of an Acetabular Cup with Improved In Vivo Stability and Integrity", Key Engineering Materials, Vols. 396-398, pp. 31-34, 2009
Online since
October 2008
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Price
$32.00
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