Paper Title:
Effect of Saline Precipitation on the Production of Collagen-Hydroxyapatite (1:1 wt%) Composite
  Abstract

Composites based on hydroxyapatite (HA) and collagen are being used for bone engineering applications. Synthetic composites were produced by precipitating hydroxyapatite in a reaction medium containing collagen fibers. The effect of saline treatment during the procedure of fibrils extraction on the composite morphology, phases presented and in vitro stability was evaluated. The FTIR analysis showed collagen bands well preserved. By Rietveld analysis, additional peaks of sodium chloride were identified on sample made from collagen submitted to saline precipitation. Besides that, the mineral formed phase is a carbonated apatite. This step during fibrils extraction results in larger areas of collagen uncoated and higher stability in culture medium. Despite of this, a cross-linking agent will be necessary to maintain the composite in culture for longer times.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
425-428
DOI
10.4028/www.scientific.net/KEM.396-398.425
Citation
D. M. Campos, L. Á. de Sena, G. D. de Almeida Soares, "Effect of Saline Precipitation on the Production of Collagen-Hydroxyapatite (1:1 wt%) Composite", Key Engineering Materials, Vols. 396-398, pp. 425-428, 2009
Online since
October 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xiao Yan Lin, Xu Dong Li, Hong Song Fan, Yu Mei Xiao, Jian Lu, Xing Dong Zhang
Abstract:Hydroxyapatite/collagen (HA/COL) composites were prepared using coprecipitation and in-situ synthesis methods. All these processes yielded...
839
Authors: H.D. Cao, Yan Fei Tan, Xiao Yan Lin, Hong Song Fan, Xing Dong Zhang
Abstract:Glutaraldehyde was increasingly used to improve the stability of the collagen-based biomaterials as cross-linking. To investigate in vitro...
223
Authors: Xu Dong Li, Xiao Min Wang, Xiao Yan Lin, Jian Ming Jiang, Xing Dong Zhang
Abstract:An organic/inorganic composite hydrogel route was used to prepare collagen-calcium phosphate hybrids with high mechanical strengths, via...
1185
Authors: Xiao Min Wang, Xu Dong Li, Gui Qiu Zheng, Xiao Liang Wang, Xing Dong Zhang, Zhong Wei Gu
Abstract:Poly(vinyl alcohol) (PVA) was introduced during in situ synthesis of hydroxyapatite (HA) in neutral collagen (COL) solution and final...
329
Authors: Xiao Liang Wang, Xu Dong Li, Xiao Min Wang, Jian Lu, Hui Chuan Zhao, Xing Dong Zhang, Zhong Wei Gu
Abstract:Collagen (Col) and chitosan (Chi) are both natural polymers and have received extensive investigation in recent years in the field of tissue...
415