New Injectable Bone Substitute Using Reversible Thermosensitive Hydrogel and BCP Granules: In Vivo Rabbit Experiments |
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| Journal | Key Engineering Materials (Volumes 396 - 398) |
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| Volume | Bioceramics 21 |
| Edited by | Marcelo Prado and Cecília Zavaglia |
| Pages | 457-460 |
| DOI | 10.4028/www.scientific.net/KEM.396-398.457 |
| Citation | Guy Daculsi et al., 2008, Key Engineering Materials, 396-398, 457 |
| Online since | October, 2008 |
| Authors | Guy Daculsi, P.A. Uzel, N. Bourgeois, T. Le François, Jean Louis Rouvillain, Xavier Bourges, Serge Baroth |
| Keywords | Biphasic Calcium Phosphate Granules, Bone Ingrowth, Self-Setting Composite, Thermosensitive Hydrogel |
| Abstract | We have developed a new injectable bone substitute combining specific granules of BCP with or without radiopaque elements with a reversible thermo sensitive resorbable carrier such as Pluronic F-127. The composite is liquid at ambient temperature and set as hydrogel at 37°C. Rabbit experiment demonstrates high biocompatibility and bone ingrowth at the expense of the injectable bioceramic composite. |
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