Current resorbable membranes are generally from animal origin, like collagen, and are largely used in dentistry or orthopaedic for TGR (Tissue Guided Regeneration), in neurosurgery for Dura matter healing and others. Calcium alginates are generally used for wound dressing (external uses). The purpose of this study was to evaluate the osteogenic property of meshes realized with calcium alginate fibers. Membrane meshes were implanted in critical size defect of rabbit femoral epiphysis during 3 and 6 weeks. Micro CT and histological analysis demonstrated biocompatibility of calcium alginate meshes in bony area. Calcium alginate meshes have no osteogenic and osteoconductive properties, however calcium alginate meshes could be a good candidate for replacement of dacron balloon used in vertebroplasty.