Paper Title:
In Vivo Performance of an Injectable Biphasic Calcium Phosphate Bone Filler
  Abstract

An hydrated putty was prepared by mixing submicron particles, rounded particles and granules of Biphasic Calcium Phosphate (BCP) ceramics composed of HA and β-TCP phases. The material filled entirely critical sized defects in the femoral epiphysis of NZW rabbits. After 3, 6 and 12 weeks, histology revealed that submicron particles were rapidly degraded by multinucleated TRAP-positive cells. This osteoclastic resorption stimulated bone ingrowth while the large BCP particles served as scaffold supporting bone healing by osteoconduction.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
583-586
DOI
10.4028/www.scientific.net/KEM.396-398.583
Citation
P. Layrolle, S. Baroth, E. Goyenvalle, E. Aguado, F. Moreau, G. Daculsi, "In Vivo Performance of an Injectable Biphasic Calcium Phosphate Bone Filler", Key Engineering Materials, Vols. 396-398, pp. 583-586, 2009
Online since
October 2008
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$32.00
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