Paper Title:
Insulin Adsorption by Hydroxyapatite
  Abstract

In this study, the insulin adsorption ability by synthetic hydroxyapatite was investigated. Hydroxyapatite before thermal treatment and heated at 900°C and 1100°C were incubated in a solution containing 32 mg insulin/gHA. Adsorption and desorption experiments were carried out at 37°C under constant and slowly stirring. From FTIR results it was observed that insulin was tightly attached to HA surface after 96 hours adsorption experiment. Thermal pre-treatment on HA samples had no effect on insulin adsorption. However, protein desorption was more pronounced on samples not submitted to thermal treatment.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
65-68
DOI
10.4028/www.scientific.net/KEM.396-398.65
Citation
E. Mavropoulos, N. C.C. da Rocha, A. M. Costa, M. H. M. Rocha-Leão, A. Mello, A. M. Rossi, "Insulin Adsorption by Hydroxyapatite", Key Engineering Materials, Vols. 396-398, pp. 65-68, 2009
Online since
October 2008
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$32.00
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