Paper Title:
Preparation and Characterization of Porous Scaffolds Consisted of Hydroxyapatite, Polysaccharides and Collagen for Cartilage Tissue Engineering
  Abstract

Porous scaffolds, consisted of hydroxyapatite (HAp), chondroitinsulfate (ChS) and collagen, were prepared by freeze-drying technique. HAp/ChS composite particles were incorporated into a collagen matrix. Scanning electron microscope (SEM) observations showed that the porous scaffolds involved interconnected pores whose size was 80~200 µm in diameter. The HAp/ChS particles were homogeneously distributed in the collagen matrix. Surface area of the scaffolds was increased by the incorporation of the particles. Compression tests in phosphate buffer saline indicated that the porous scaffolds had elastic property and had larger compressive modulus than the pure collagen scaffold. The porous scaffolds obtained in this study could be useful for a cartilage tissue engineering.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
707-710
DOI
10.4028/www.scientific.net/KEM.396-398.707
Citation
T. Adegawa, Y. Ohyabu, T. Uemura, T. Yoshioka, K. Shinozaki, M. Tanaka, "Preparation and Characterization of Porous Scaffolds Consisted of Hydroxyapatite, Polysaccharides and Collagen for Cartilage Tissue Engineering ", Key Engineering Materials, Vols. 396-398, pp. 707-710, 2009
Online since
October 2008
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Price
$32.00
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