In the course of present space lander’s optimization, the problems, such as hardness of information integration, partiality of optimization, still exist. In order to solve these problems, Lander Multidisciplinary Optimization Platform has been built. Four engineering tools (Pro/Engineer, Patran, Nastran, ADAMS) are integrated into the platform based on optimization software—iSIGHT, which could ensure space lander’s kinematics and dynamics characteristics. Good optimum scheme is obtained after comprehensive optimization of the platform. Besides, the platform is managed by simulation management software—MSC.SimManage. Multidisciplinary optimization can be realized automatically through parameterized interface of the platform.