To satisfy the requirement in blisk machining, a barrel-ball milling (BBM) cutter suitable for machining both blade and hub is presented in this paper. The selection of cutter parameter and calculation of cutter location were put forward. The new efficient machining cutter location via the advanced optimization on cutter machining strip width was gained. By the numerical simulation of blisk blade machining, the feasibility of the BBM cutter and cutter location strategy were verified. The result showed that the efficiency of this method was increased to more than three times compared to the machining with a ball cutter.