Sheet hydroforming has gained increasing interest in the automotive and aerospace industries because of its many advantages such as higher forming potentiality, good quality of the formed parts which may have complex geometry. The main advantage is that the uniform pressure can be transferred to any part of the formed blank at the same time . In this paper, a “shape factors” set has been defined with the proper goal to understand if it can be used to help engineers to define “process rules” for the studied non conventional technology . A specific prediction model, obtained thanks to a numerical factorial fractional plane, has been used in order to preview the process responses vs each defined shape factor. These shape factors have been used to track the process performances through their variation thanks to the usage of the numerical simulation that has been validated with an appropriate experimental campaign executed thanks to the usage of a specific equipment properly designed.