The seismic performance and seismic damage model for steel reinforced high strength and high performance concrete (SRHSHPC) composite frame columns subjected to constant axial load and cyclically variety flexural loading was investigated experimentally. The main influencing parameters, including shear span ratio, axial compression ratio, stirrup ratio and concrete strength, on the seismic performance and seismic damage of the SRHSHPC frame columns is studied. From the test results, the failure mechanism is analyzed and damage quantization criterion is obtained. Several existing seismic damage models are comparatively analyzed. And then, the variation history of accumulated hysteretic energy of the specimens under different loading cycle indexes is figured out, and influence of different test parameters on it is also discussed. Finally, the damage index of the SRHSHPC columns is compared to the existing seismic damage models, and the double variables seismic damage model adapted for the SRHSHPC structure is established by statistical regression theory. The rule of damage evolvement for the specimens is proposed employing variation history of the damage index under different loading cycle indexes. The analytical results indicate that the seismic performance of the SRHSHPC composite column is good, and the double variables damage model could give a quantitative description for damaging process of the samples, which is a reference for seismic damage design of the SRHSHPC structure.