In this paper, based on CFD method and dynamic mesh technology, the ship maneuvering performance is predicted in viscous flow. Numerical computation models are built to realize the simulation of the ship maneuvering motions such as static drift test, static rudder test, pure yaw test and pure sway test. Hydrodynamic forces and moments acting on a maneuvering ship are obtained in the body-fixed coordinate system. The computational results are compared with data of potential theory method. Then based on VC code, a simulator of ship maneuvering motions is built to simulate ship Zigzagging and Turing test. The results show that the present numerical simulation method and the ship maneuvering motion simulator are able to be used in numerical simulation of the real size ship maneuvering motions in viscous flow field.