Paper Title:
Functionalized Calcium Phosphate Nanoparticles for Biomedical Application
  Abstract

Calcium phosphate is a natural biomineral and therefore possesses an excellent biocompatibility due to its chemical similarity to human hard tissue (bone and teeth). Calcium phosphate nanoparticles can be precipitated under controlled conditions and used as carrier in biological systems, e.g. to transfer nucleic acids or drugs. Such nanoparticles can also be suitably functionalized with fluorescing dyes, polymeric agents, pro-drugs or activators. The small monodisperse nanoparticles only mildly influence the intracellular calcium level and therefore are not toxic for cells.

  Info
Periodical
Edited by
M. Vallet-Regí and M. Vila
Pages
299-305
DOI
10.4028/www.scientific.net/KEM.441.299
Citation
M. Epple, A. Kovtun, "Functionalized Calcium Phosphate Nanoparticles for Biomedical Application", Key Engineering Materials, Vol. 441, pp. 299-305, 2010
Online since
June 2010
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