In order to investigate the mechanical effects during pulsed laser and metal target in neutral solution, a measuring part of stainless cantilever was developed. The vibration of the stainless cantilever was tested and analyzed based on the test mechanism of piezoelectric accelerometer. The impact pressure of the target in NaNO3 solution by pulsed lasers at wavelength of 532nm and 1064nm with millisecond pulse duration were obtained by the test with the measuring part. The results show that mechanical effect during pulsed laser and stainless target interaction in neutral solution is more than three times higher than in air. The pressure of the target with infrared laser is decreased with the distance of laser propagation in neutral solution. However, the effect with green laser is stable in the laser transmission range of 20mm. The green laser is more suitable for processing under neutral solution.