This paper was devoted to the numerical simulation the resin curing process. Anisotropic conduction was considered in the model. And Kamal-Ryan model was used to describe the curing kinetics of the resin. The general purpose finite element code ABAQUS was used in conjunction with its user subroutine UMATHT to solve the heat conduction equation and the kinetic model, simultaneously. Then corresponding experiment was carried out to validate the model. Finally, rate-of-cure, temperature and state-of-cure were analyzed during the curing process.