Paper Title:
Preparation and Characterization of Chitosan-Casein Phosphopeptides Biocomposite Coatings on the Medical Titanium Alloy
  Abstract

Titanium (Ti) and its alloys have been applied in orthopedics as one of the most popular biomedical metallic implant materials. In this work, to enhance the bioactivity, the surface of Ti alloy pre-modified by silane coupling agent and glutaraldehyde was covalently grafted with chitosan (CS) via biochemical multistep self-assembled method. Then, for the first time, the achieved surface was further immobilized with casein phosphopeptides (CPP), which are one group of bioactive peptides released from caseins in the digestive tract and can facilitate the calcium adsorption and usage, to form CS-CPP biocomposite coatings. The structure and composition of the fabricated coatings were characterized by X-ray photoelectron spectroscopy (XPS), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and atomic force microscopy (AFM). As the experimental results indicated, multi-step assembly was successfully performed, and the CS and CPP were assembled onto the Ti alloy surface orderly. It is anticipated that the Ti alloys modified by CS-CPP biocomposite coatings will find potential applications as implant materials in biomedical fields.

  Info
Periodical
Key Engineering Materials (Volumes 480-481)
Edited by
Yanwen Wu
Pages
1065-1069
DOI
10.4028/www.scientific.net/KEM.480-481.1065
Citation
B. Liu, L. Wang, Y. Z. Bu, S. R. Yang, J. Q. Wang, "Preparation and Characterization of Chitosan-Casein Phosphopeptides Biocomposite Coatings on the Medical Titanium Alloy", Key Engineering Materials, Vols. 480-481, pp. 1065-1069, 2011
Online since
June 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: S.M. Yang, Suk Young Kim, Seung Jin Lee, Yong Keun Lee, Young Min Lee, Y. Ku, Chong Pyong Chung, S.B. Han, I.C. Rhyu
245
Authors: Ying Peng, Jian Ping Deng, Wan Tai Yang
Abstract:Lithium acrylate (LiAA) was applied as a functional monomer to modify the surface properties of polypropylene films via photografting...
359
Authors: Zhong Jun Wang, Yang Xu, Jing Zhu
Abstract:The microstructures and corrosion resistance of AZ91 and AZ91+0.5 wt.% erbium (Er) magnesium alloys were studied, respectively. The results...
1221
Authors: Kee Do Woo, Sang Hoon Park, Ji Young Kim, Sang Mi Kim, Dong Soo Kang
Chapter 10: Biomaterials
Abstract:Ti-6Al-4V ELI (Extra Low Interstitial) alloy have been widely used as alternative bone due to its excellent biocompatibility, although it...
1592
Authors: Kee Do Woo, Sang Hoon Park, Ji Young Kim
Chapter 1: Advance in Composite Material
Abstract:Ti-6Al-4V ELI (Extra Low Interstitial) alloy have been widely used as alternative bone due to its excellent biocompatibility, although it...
12