Paper Title:
Biocompatibility of Carbonated Hydroxyapatite Nanoparticles with Different Crystallinities
  Abstract

Carbonated apatite (CHA) is commonly considered a promising synthetic material for biomedical applications in orthopedic and dental surgery due to its biocompatibility, bioresorption and bioactivity. CHA5, CHA37 and CHA90 powders were synthesized from wet method and the DRX patterns showed that the crystallinity and particle size of CHA samples increased proportionally with the synthesis temperature. Powder extracts medium were obtained from each sample to interact with MC3T3-E1 osteoblastics cells. It was evaluated morphology, citotoxicity, pH and Ca2+ concentration. Citotoxicity assays showed high metabolic activity on all samples when compared to control. The polygonal shaped and the confluent monolayer observed in control cells progressively changed according to the crystallinity increase of samples. Cells under mitosis and spindle-like shaped where the main alterations observed. In addition the cell viability could be sensitive to the acid reactivity and crystallinity of carbonated apatite samples.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
331-336
DOI
10.4028/www.scientific.net/KEM.493-494.331
Citation
E. Mavropoulos, M. Hausen, A. M. Costa, S. R. Albuquerque, G. Alves, J.M. Granjeiro, A. M. Rossi, "Biocompatibility of Carbonated Hydroxyapatite Nanoparticles with Different Crystallinities", Key Engineering Materials, Vols. 493-494, pp. 331-336, 2012
Online since
October 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Raden Dadan Ramdan, Iswadi Jauhari, Rafidah Hasan, Nik Rozlin Nik Masdek, Fadzil Ayad Zakaria, K. Jamuna
Abstract:The effect of carbonated apatite powder size on the carbonated apatite embedded on titanium alloy was studied. The process was conducted...
785
Authors: Masazumi Okido, Ryoichi Ichino, Kotaro Kuroda
Abstract:Hydroxyapatite (Ca10(PO4)6(OH)2, HAp), carbonated HAp and titanium oxide are of interest for bone-interfacing implant applications, because...
687
Authors: Shigeki Matsuya, Michito Maruta, Kanji Tsuru, Ishikawa Kunio
III. Cements
Abstract:Carbonate apatite showed an excellent bioresorbability through the remodeling process of bone. In the present study, we prepared self-setting...
197
Authors: Son Tung Pham, William Prince
II: Building Materials and Technologies in Construction
Abstract:The objective of this work was to examine the microstructural changes caused by the carbonation of normalised cement mortar. Samples were...
411