Paper Title:
Fabrication of Janus Microfiber in Microfluidic System
  Abstract

This study presents a novel synthetic approach for the preparation of cell attachable microfibers in microfluidic system. The synthesis is performed by multiphase laminar flows with spontaneous formation of carbon dioxide bubbles resulting asymmetrically porous PU microfiber. The fabricated Janus microfiber provides two distinctive properties: one is porous region to promote the cellular adhesion and the other is nonporous region rendering mechanical strength of the scaffold. The Janus microfibers show dramatic improvement of cell adhesion, proliferation, and viability over a culture period. The Janus microfiber can be used for not only alternative 2D cell culture plate but also as novel 3D scaffold for tissue engineering wihtout any need of elegant surface modification for enhancing cell adhesions.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
343-348
DOI
10.4028/www.scientific.net/KEM.493-494.343
Citation
H. H. Jeong, S. H. Lee, C. S. Lee, "Fabrication of Janus Microfiber in Microfluidic System", Key Engineering Materials, Vols. 493-494, pp. 343-348, 2012
Online since
October 2011
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Price
$35.00
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