Paper Title:
Ion Release Behavior and Apatite-Forming Ability of Sol-Gel Derived 70S30C Bioactive Glass with Magnesium/Zinc Substitution
  Abstract

Bioactive glasses not only can bond to hard tissues of the body, are also able to release ions that have stimulatory effects on cells and so are regarded as promising candidate materials for gene activating purposes in tissue engineering applications. In this research the effect of co-substitution of Magnesium and Zinc for Calcium on bioactivity of binary sol-gel derived glass 70S30C (70 mol. % SiO2, 30 mol. % CaO) was investigated. Calcium phosphates forming ability tests and investigation of glass degradation products in simulated body fluid (SBF) were performed as follows.After sol-gel synthesis of glass powders of comparable and under 38 μm particle size distributions, their state of being amorphous was investigated using X-ray diffraction. Then for in vitro investigation of bioactivity, ion release, pH change and Calcium phosphate formation during immersion of glass powders in SBF at 37 ͦ C up to 2 weeks were studied. Infrared spectroscopy was performed on the reacted glass powders.Results indicate that substitution of Zinc for Calcium suppresses crystalline apatite formation more effectively than substitution of Magnesium for Calcium and help us design modified compositions of magnesium and zinc containing bioactive glasses that can find applications in bone and also cartillage tissue engineering.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
55-60
DOI
10.4028/www.scientific.net/KEM.493-494.55
Citation
A.A. Hamedani, F. Moztarzadeh, D. Bizari, M. Ashuri, M. Tahriri, "Ion Release Behavior and Apatite-Forming Ability of Sol-Gel Derived 70S30C Bioactive Glass with Magnesium/Zinc Substitution", Key Engineering Materials, Vols. 493-494, pp. 55-60, 2012
Online since
October 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: R.S. Pryce, Larry L. Hench
201
Authors: Chikara Ohtsuki, H. Inada, Masao Tanihara, Masanobu Kamitakahara, Toshiki Miyazaki
59
Authors: Priya Saravanapavan, Julie E. Gough, Julian R. Jones, Larry L. Hench
1087
Authors: R. Sindut, Katarzyna Cholewa-Kowalska, Maria Łączka
Abstract:Bioglasses and bioactive glass-ceramics have found increasingly wide application in medicine and dentistry. Using sol-gel method, is...
103
Authors: Dan Nicolae Ungureanu, Nicolae Angelescu, Adrian Catangiu, Elena Valentina Stoian, Cristiana Zizi Rizescu, Daniela Avram
Abstract:Bioactive glasses based on SiO2-CaO-P2O5 system have been synthesized by sol – gel process. The powder glass...
21