Paper Title:
Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties
  Abstract

Hybrids of hydroxyapatite (HAp) and poly(L-lactic co glycolic) (PLGA) have been fabricated, which can be expected to be a novel filler for bone grafting. The porous HAp ceramics with bimodal pore structure have been fabricated from apatite fibers synthesized by homogeneous precipitation method. Then, HAp/PLGA hybrids have been fabricated by introducing PLGA having high molecular-weight into the open pores of the porous HAp ceramics. Total porosities of the porous HAp ceramics slightly decreased from 71.5% down to 67.4% after infiltrating PLGA into the porous HAp ceramics. The bending strength of the HAp/PLGA hybrids was ~ 8.3 MPa. The value attained about 2 times that of the porous HAp ceramics.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
556-560
DOI
10.4028/www.scientific.net/KEM.493-494.556
Citation
N. Osada, Y. Shigemitsu, M. Makita, K. Oribe, M. Aizawa, "Fabrication of Organic/Inorganic Hybrids by Infiltration of Commercially-Available PLGA into Porous Hydroxyapatite Ceramics and its Material Properties", Key Engineering Materials, Vols. 493-494, pp. 556-560, 2012
Online since
October 2011
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