Paper Title:
Silicate and Calcium Ions Releasing Biomaterials for Bone Reconstruction
  Abstract

Siloxane-containing vaterite (SiV) / poly (lactic acid) hybrid (SiPVH) beads with the releasability of silicate and calcium ions were prepared with an electrospraying method. According to the increase in the silicon content of the SiV, the amount of silicate ion released from the resulting beads also increased. When the beads were soaked in a cell culture medium, proteins derived from fetal bovine serum were adsorbed on their surfaces. Cell adhesion tests were also performed on the beads with using mouse osteoblast-like cell line (MC3T3-E1) in vitro. After 5 days of culturing, the cells adhered and spread well to cover the surface of the beads. In the localized area, agglomerated cells were observed to combine with cauliflower-shaped calcium phosphate deposits.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
561-565
DOI
10.4028/www.scientific.net/KEM.493-494.561
Citation
J. Nakamura, A. Obata, J. R. Jones, T. Kasuga, "Silicate and Calcium Ions Releasing Biomaterials for Bone Reconstruction", Key Engineering Materials, Vols. 493-494, pp. 561-565, 2012
Online since
October 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Kay Teraoka, Takao Saito, Yoshiyuki Yokogawa
Abstract:This paper demonstrated a simple technique to seed the hydroxyapatite (HA) ceramic with 2-D cultured cells to establish an advanced mode of...
683
Authors: Mamoru Aizawa, A. Hiramoto, H. Maehashi, Tomokazu Matsuura
Abstract:We have previously developed apatite-fiber scaffolds (AFSs) for bone tissue engineering using single-crystal apatite fibers and carbon...
1165
Authors: Teruo Asaoka, Yuji Kajihata, Katsuko Furukawa, Takashi Ushida, Tetsuya Tateishi
Abstract:As excellent scaffolds for cultivating bone cells, porous beads of bioactive ceramics such as HAp, TCP are considered to be promising. HAp...
2021
Authors: Fan Xiao, Fei Gao, Zhi Xian Zhang, Wei Li
Abstract:Alginate/silica composite beads of mm-size for biomedical applications were prepared from water glass and sodium alginate via a simple...
1889
Authors: A. Tamura, Teruo Asaoka, K. Furukawa, T. Ushida, T. Tateishi
Chapter 3: Tissue Engineering and Regenerative Medicine
Abstract:α-TCP/HAp functionally graded porous beads were prepared for use as a scaffold for bone regeneration. In this research, porous beads which...
63