Paper Title:
Poly(lactic-co-glycolic)/Nanostructured Merwinite Porous Composites for Bone Tissue Engineering. I. Preparation and Morphology
  Abstract

A novel merwinite/ Poly(lactic-co-glycolic) nanocomposite was synthesized by a solvent casting/salt leaching technique with varying merwinite contents from 10 to 30% (w/w). Poly(lactic-co-glycolic) /merwinite foams with a co-continuous structure of interconnected pores were formed. The microstructure of the pores and the walls was controlled by varying the merwinite content. The pore structure becomes more and more irregular with increasing merwinite content. Pore sizes ranging from several microns to a few hundred microns were obtained. The degradation assessment of the scaffolds is performed in phosphate-buffered saline (PBS) solution at 37°C. Weight loss during storage at 37°C in PBS (pH 7.4) was determined for the scaffolds. Weight loss increased from pure to high content during incubation time. The prepared merwinite/ (Polylactic-co-glycolic) nanocomposite with uniform microstructure may be used in bone tissue engineering applications.

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
718-722
DOI
10.4028/www.scientific.net/KEM.493-494.718
Citation
M. Hafezi-Ardakani, F. Kavian, F. Moztarzadeh, M. B. Eslaminejad, A. Zamanian, F. Bagheri, "Poly(lactic-co-glycolic)/Nanostructured Merwinite Porous Composites for Bone Tissue Engineering. I. Preparation and Morphology", Key Engineering Materials, Vols. 493-494, pp. 718-722, 2012
Online since
October 2011
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Price
$32.00
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