Paper Title:
Effect of Silver Concentration on Bioactivity and Antibacterial Properties of SiO2-CaO-P2O5 Sol-Gel Derived Bioactive Glass
  Abstract

Human beings are often infected by microorganisms in the living environment. Among various natural and inorganic substances, silver or silver ions have a powerful antibacterial activity. In the present study, the bioactivity and antibacterial activity of the SiO2–CaO–P2O5–Ag2O was compared with that of its ternary counterpart glass system (as a control sample) in vitro. The molar ratio of silver oxide in the bioactive glass composition was considered as different amount (0.5%, 1% and 2%). The surface characterization was evaluated after soaking in simulated body fluid (SBF). The sharpest apatite peak in X-ray diffraction (XRD) analyse after 7 days soaking in SBF was observed for 2% Ag sample (2%Ag-BG). Hence, the antibacterial effects of 2%Ag-BG sample against 2 gram negatives bacterium were examined by agar plate test. The result showed that the amount of silver did not prevent the HAp formation. Also, the antibacterial properties of 2%Ag-BG sample indicated near 100% bactericidal ratio (according to the width of antibacterial halo).

  Info
Periodical
Key Engineering Materials (Volumes 493-494)
Main Theme
Edited by
Eyup Sabri Kayali, Gultekin Goller and Ipek Akin
Pages
74-79
DOI
10.4028/www.scientific.net/KEM.493-494.74
Citation
N. Nezafati, F. Moztarzadeh, S. Hesaraki, M. Mozafari, A. Samadikuchaksaraei, L. Hajibaki, M. Gholipour, "Effect of Silver Concentration on Bioactivity and Antibacterial Properties of SiO2-CaO-P2O5 Sol-Gel Derived Bioactive Glass", Key Engineering Materials, Vols. 493-494, pp. 74-79, 2012
Online since
October 2011
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$32.00
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