Effect of Silver Concentration on Bioactivity and Antibacterial Properties of SiO2-CaO-P2O5 Sol-Gel Derived Bioactive Glass
| Periodical | Key Engineering Materials (Volumes 493 - 494) |
|---|---|
| Main Theme | Bioceramics 23 |
| Edited by | Eyup Sabri Kayali, Gultekin Goller and Ipek Akin |
| Pages | 74-79 |
| DOI | 10.4028/www.scientific.net/KEM.493-494.74 |
| Citation | Nader Nezafati et al., 2011, Key Engineering Materials, 493-494, 74 |
| Online since | October, 2011 |
| Authors | Nader Nezafati, Fathollah Moztarzadeh, Saeed Hesaraki, Masoud Mozafari, Ali Samadikuchaksaraei, Leila Hajibaki, Mazaher Gholipour |
| Keywords | Agar Plate Test, Antibacterial Properties, Bioactive Glass, Gram Negatives Bacterium, Silver |
| Price | US$ 28,- |
Human beings are often infected by microorganisms in the living environment. Among various natural and inorganic substances, silver or silver ions have a powerful antibacterial activity. In the present study, the bioactivity and antibacterial activity of the SiO2–CaO–P2O5–Ag2O was compared with that of its ternary counterpart glass system (as a control sample) in vitro. The molar ratio of silver oxide in the bioactive glass composition was considered as different amount (0.5%, 1% and 2%). The surface characterization was evaluated after soaking in simulated body fluid (SBF). The sharpest apatite peak in X-ray diffraction (XRD) analyse after 7 days soaking in SBF was observed for 2% Ag sample (2%Ag-BG). Hence, the antibacterial effects of 2%Ag-BG sample against 2 gram negatives bacterium were examined by agar plate test. The result showed that the amount of silver did not prevent the HAp formation. Also, the antibacterial properties of 2%Ag-BG sample indicated near 100% bactericidal ratio (according to the width of antibacterial halo).
