Paper Title:

In Situ Time-Resolved Energy Dispersive X-Ray Diffraction Studies of Calcium Phosphate Based Bone Cements

Periodical Key Engineering Materials (Volume 541)
Main Theme Bone and Biomaterials for Bone Tissue Engineering
Chapter II. Innovative Characterisation Technique for Bone Tissue Engineering
Edited by Alessandra Bianco, Ilaria Cacciotti and Ilaria Cappelloni
Pages 115-120
DOI 10.4028/
Citation Julietta V. Rau et al., 2013, Key Engineering Materials, 541, 115
Online since February 2013
Authors Julietta V. Rau, Marco Fosca, Vladimir S. Komlev
Keywords Bone Cement, Bone Substitute Materials, Dicalcium Phosphate Dihydrate, Energy Dispersive X-Ray Diffraction, Hydroxyapatite (HAP), Octacalcium Phosphate, Phase Transformation, Simulated Body Fluid (SBF)
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In situ monitoring of structural changes, taking place upon calcium phosphate bone cements hardening process was carried out by means of the Energy Dispersive X-Ray Diffraction method. Two different cement systems were studied, one of them based on the octacalcium phosphate and another - on the dicalcium phosphate dehydrate. Both systems contained natural biopolymer chitosan and were soaked in Simulated Body Fluid. The obtained experimental results evidence that during the hardening of the cement containing octacalcium phosphate its partial transformation into hydroxyapatite takes place, whereas no significant changes were detected during the hardening process of cement containing the dicalcium phosphate dehydrate.