In the present paper, the relationship between characteristic wave impedance and compositions was mainly investigated in order to find a suitable theoretical model for predicting the impedance value of Ti-Mo system composites and FGM. At first, dense Ti-Mo composites with different weight fractions of Mo were prepared. Then the transverse and longitudinal wave velocities of the samples were measured and the characteristic wave impedance values were obtained. A mixture model was adopted to estimate the characteristic wave impedance value of Ti-Mo composites. Comparisons between the estimated and experimental results demonstrated that the suggested model was sufficiently accurate to predict the characteristic wave impedance value of Ti-Mo system composites and FGM.