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Compare of Electrospinning PLA and PLA/β-TCP Scaffold in Vitro

Journal Materials Science Forum (Volumes 475 - 479)
Volume PRICM-5
Edited by Z.Y. Zhong, H. Saka, T.H. Kim, E.A. Holm, Y.F. Han and X.S. Xie
Pages 2379-2382
DOI 10.4028/www.scientific.net/MSF.475-479.2379
Citation Hong Song Fan et al., 2005, Materials Science Forum, 475-479, 2379
Online since January, 2005
Authors Hong Song Fan, Xian Tao Wen, Yan Fei Tan, R. Wang, H.D. Cao, Xing Dong Zhang
Keywords Composite Materials, Electrospinning, Poly(lactic acid) (PLA), Scaffold
Abstract

In recent years, electrospinning process is gradually applied in producing tissue-engineering scaffold. In this study, we chose polylacticacid(PLA) and β-tertiary calcium phosphate(β-TCP) as raw materials to fabricate PLA/β-TCP biodegradable composite scaffold by electrospinning process. The characteristics of the scaffold and effect of the scaffolds to cell proliferation and cell adhesion was studied. Compare with pure PLA scaffold, blendingβ-TCP in the spinning process of the scaffold could improve the properties of the scaffold, especially the hydrophilicity and the proliferation and adhesion of cells, this means that the material is more potential to be used as tissue engineering scaffolds.

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