Paper Title:
Biocompatibility of Polyethylene Doped with Oxycellulose
  Abstract

Physical and chemical properties of polyethylene (PE) films doped with calcium salt of oxycellulose (Ca-oxy) and its interaction with cells in culture conditions were studied. The samples with various concentrations of Ca-oxy (0-20 %) were prepared. Samples were tested by goniometer measurements, X-ray diffraction, FTIR spectroscopy and SEM. Sample weight changes during boil sterilization and adhesion and proliferation of tissue cells (3T3 mouse fibroblasts) were studied. It was found that wetting angle of the doped films decreased with increasing Ca-oxy concentration to up to 10% and then increased again. Both film surfaces had different amount of crystalline phase, thereby different surface roughness. Due to a smaller surface roughness, cell growth was much better on the inner surface of the film than on the outer one. Cells adhered better to samples with 1% of Ca-oxy and with a higher content of oxycellulose over 7%. Cell proliferation was the best on samples with 1-5% Ca-oxy. Samples were polished to modify their surface roughness. Polishing increased cell proliferation especially on samples with a lower Ca-oxy concentration (1-5%).

  Info
Periodical
Edited by
Jaroslav Pokluda
Pages
251-254
DOI
10.4028/www.scientific.net/MSF.482.251
Citation
R. Mikulíková, K. Kolářová, L. Bačáková, V. Švorčík, "Biocompatibility of Polyethylene Doped with Oxycellulose", Materials Science Forum, Vol. 482, pp. 251-254, 2005
Online since
April 2005
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$32.00
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