Paper Title:
Removal of Bilirubin by Albumin-Fixed Polysulfone Membrane
  Abstract

An asymmetric polysulfone membrane with reactive group of –OH was obtained by hydrolyzing the chloromethylated polysulfone membrane, and the albumin molecules were immobilized into the membrane with a crosslinking reagent of 1,4-butanediol diglycidyl ether. The albumin-fixed membrane was used to remove lipophilic toxins, bilirubin, from the bilirubin-albumin solution. The experiment results showed that the transfer rate of bilirubin was clearly enhanced after fixing albumin into the hydroxylated polysulfone membranes. The clearance of bilirubin was 49.3%. In addition, the effect of membrane thickness on the removal of bilirubin is discussed.

  Info
Periodical
Materials Science Forum (Volumes 510-511)
Edited by
Hyung Sun Kim, Yu Bao Li and Soo Wohn Lee
Pages
682-685
DOI
10.4028/www.scientific.net/MSF.510-511.682
Citation
D. T. Ge, W. Shi, L. Ren, Q. Q. Zhang, "Removal of Bilirubin by Albumin-Fixed Polysulfone Membrane", Materials Science Forum, Vols. 510-511, pp. 682-685, 2006
Online since
March 2006
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Price
$32.00
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