Paper Title:
Evaluation of Cytotoxic Activity of d-Metal Complexes with Hydrazone Ligands
  Abstract

Cytotoxic activity of four series of coordinated complexes of Zn(II) and Fe(II) with hydrazone/hydrazide ligands against HeLa and B16 cells was evaluated. The ligands N’,N'2- bis[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (H2L1) and N’,N'2-bis[(1E)-1-(2-pyridyl) ethylidene]propanedihydrazide (H2L2) and their Zn(II) complexes showed IC50 values in the low micromolar range, while the other ligands and complexes were less active or inactive.

  Info
Periodical
Edited by
Dragan P. Uskokovic, Slobodan K. Milonjic and Dejan I. Rakovic
Pages
513-518
DOI
10.4028/www.scientific.net/MSF.518.513
Citation
M. Lazić, S. Radulović, T. R. Todorović, D.M. Sladić, Ž. Tešić, K.K. Andjelković, "Evaluation of Cytotoxic Activity of d-Metal Complexes with Hydrazone Ligands", Materials Science Forum, Vol. 518, pp. 513-518, 2006
Online since
July 2006
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