Paper Title:
Polyamine Group Assembled Silica Coated Ferrite Nanoparticle or Lambda DNA Detection
  Abstract

This study describes the development of a high throughput purification process of nucleic acid using amino-functionalized silica coated ferrite nanoparticles. The magnetic ferrite nanoparticles were synthesized and coated by a silica precursor in controlling the coating thicknesses and sizeses. The surface modification was performed with amino-functionalized organic silanes on silica coated magnetic nanoparticles. The spectroscopic measurements such as a FT-IR (ATR-method) and Vibrational Sample Magnetometer (VSM) were used to characterize the chemical structures and magnetic strengths. To elucidate the relationship between surface area, pore size distribution and reactivity of the materials, BET and Zeta potential were used. The use of functionalized self-assembled magnetic ferrite nanoparticles for a nucleic acid separation process provides a lot of advantages compared to the conventional silica based process.

  Info
Periodical
Materials Science Forum (Volumes 534-536)
Edited by
Duk Yong Yoon, Suk-Joong L. Kang, Kwang Yong Eun and Yong-Seog Kim
Pages
1357-1360
DOI
10.4028/www.scientific.net/MSF.534-536.1357
Citation
M. E. Park, J. H. Chang, "Polyamine Group Assembled Silica Coated Ferrite Nanoparticle or Lambda DNA Detection", Materials Science Forum, Vols. 534-536, pp. 1357-1360, 2007
Online since
January 2007
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Price
$32.00
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