Paper Title:
Biofunctional Materials for Nerve Regeneration
  Abstract

Most biomaterials widely used in nerve regeneration are either inert or modified with ECM proteins or their epitopes. Neurotransmitters play a key role in neuronal development and function. Thus we decided to investigate the feasibility of using neurotransmitters to create biofunctional materials that actively engage nerve cells to achieve functional restoration after injury of the nervous system. Our data indicated that a properly designed biodegradable polymer with dopamine functional groups was more capable of promoting neurite growth. Such biofunctional materials can potentially provide a new strategy for nerve regeneration.

  Info
Periodical
Materials Science Forum (Volumes 539-543)
Main Theme
Edited by
T. Chandra, K. Tsuzaki, M. Militzer , C. Ravindran
Pages
547-550
DOI
10.4028/www.scientific.net/MSF.539-543.547
Citation
Y. M. Kim, J. Gao, B. Zern, Y. D. Wang, "Biofunctional Materials for Nerve Regeneration", Materials Science Forum, Vols. 539-543, pp. 547-550, 2007
Online since
March 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Gui Gen Zhang, Furqan Haq, Anandan Venkatramani
Abstract:We investigated the role of substrate topography on neurite development in pheochromocytoma (PC12 cells) by culturing the cells on...
85
Authors: Seeram Ramakrishna, Jayarama Reddy Venugopal, Susan Liao
Abstract:Attempts have been made to fabricate nanofibrous scaffolds to mimic the chemical composition and structural properties of extracellular...
114
Authors: Vincenzo Guarino, Antonio Gloria, Marco A. Alvarez-Perez, Maria Grazia Raucci, Valentina Cirillo, Alfredo Ronca, Roberto De Santis, Luigi Ambrosio
Plenary and Invited Speakers
Abstract:In order to mimic the behaviors of natural tissue, the optimal approach for designing novel biomaterials has to be inspired to nature...
8
Authors: Asiful Islam, Latika Menon
Chapter 14: Nanomaterials and Nanomanufacturing
Abstract:The anodization of aluminum templates created nanoporous alumina tubes arranged parallel to each other and electrodeposition using gold...
3863
Authors: Ping Zhang, Shan Shan Wu
Chapter 1: Applied Materials Engineering and Materials Processing
Abstract:Nanofibers produced by electrospinning represent a new class of promising scaffolds to support nerve regeneration. Here, we found that the...
95