Paper Title:
Trivalent and Hexavalent Chromium Issues in Medical Implants
  Abstract

Metal alloys containing chromium (Cr), primarily stainless steels and CoCr alloys, are used in a wide variety of implantable medical devices. These alloys are exposed to chloride containing environments with varying oxidizing potential and complexing agents. These corrosion assisted environmental effects may result in metal ions going into solution. The toxicity of Cr is dependent on valence state. Hexavalent Cr ions are recognized to be more toxic than trivalent Cr. This paper discusses the state of knowledge regarding Cr release, the chemical and mechanical factors that most significantly affect Cr release, and the potential toxicity of Cr as it applies to longterm implantable medical devices.

  Info
Periodical
Materials Science Forum (Volumes 539-543)
Main Theme
Edited by
T. Chandra, K. Tsuzaki, M. Militzer , C. Ravindran
Pages
698-703
DOI
10.4028/www.scientific.net/MSF.539-543.698
Citation
L. E. Eiselstein, D.M. Proctor, T.C. Flowers, "Trivalent and Hexavalent Chromium Issues in Medical Implants", Materials Science Forum, Vols. 539-543, pp. 698-703, 2007
Online since
March 2007
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