Superplastic behavior and microstructure evolution of an isothermally forged Ti-47Al-1Cr-1V-1.5Mo-1.5Nb alloy were investigated. The results showed that the strain rate sensitivity index, m, increased with strain during the superplastic deformation, and it kept as a constant when the strain reached a certain value. The maximum value of m was 0.53 at 900°C and strain rate of 5x10-4 s-1. During the superplastic deformation, the as received material with lamellae and subgrains were refined due to dynamic recrystallization, and small and equiaxed grains with high angle boundaries were formed, creating a better condition for superplastic deformation. Grain boundary sliding and boundary migration were the main superplastic deformation mechanisms and slip and twining were also very important during the superplastic deformation of the alloy.