Explosive cladding is a non-conventional, solid-phase bonding technique in which bonding between two plates is produced by their high velocity collision induced by the use of explosives. Attempts were made to explosive clad Titanium-Stainless steel (SS 304 L) plates (3.5 and 3.0 mm thick respectively). The experiments were designed to analyze the bonding interface parallel to the detonation direction. The presence of intermetallics, caused by the melting at the interface due to kinetic energy dissipation, was observed in some locations. The process parameters of the explosive welding of Titanium-Stainless steel combination are defined using the microstructural observations, microhardness at the interface, the results of X-ray diffraction study. A weldability window is also constructed for explosive welding of Ti /Ss.