Influence of biaxial stress applied perpendicularly to the  loading axis on the tensile stress-strain response is studied from first principles. Crystals of four cubic metals Mo, W, Ir and Au were selected as particular case studies. The results obtained show that, within a limited range of biaxial stresses, the tensile stress increases almost linearly with increasing transverse biaxial stress. The factor that expresses the slope of the linear function changes with applied tensile strain. A region of tensile stability of cubic crystals is also discussed.