Paper Title:
Rheology of Chitosan and Genipin Solutions
  Abstract

This paper investigates the rheological behaviour of chitosan solutions crosslinked with different concentrations of genipin at body temperature and physiological pH. The effect of the crosslinker concentration on the rheological properties of hydrogels was evaluated. The oscillatory time sweep was used to analyze the dynamics of G’ during in situ gelation experiments enabling the determination of the gelation time. Additionally, the stress and frequency sweeps were employed to measure G’ of cured hydrogels. The solutions of chitosan crosslinked with genipin at physiological conditions were found to form relatively strong elastic gels for all the concentrations, when compared to pure chitosan. A significant reduction on gelation time was achieved. This behaviour shows that these formulations are able to be produced in situ and thus constitute promising matrices for cells and bioactive molecules encapsulation.

  Info
Periodical
Materials Science Forum (Volumes 587-588)
Edited by
António Torres Marques, António Fernando Silva, António Paulo Monteiro Baptista, Carlos Sá, Fernando Jorge Lino Alves, Luís Filipe Malheiros and Manuel Vieira
Pages
27-31
DOI
10.4028/www.scientific.net/MSF.587-588.27
Citation
M.J. Moura, M.M. Figueiredo, M. H. Gil, "Rheology of Chitosan and Genipin Solutions", Materials Science Forum, Vols. 587-588, pp. 27-31, 2008
Online since
June 2008
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Price
$32.00
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