Paper Title:
Silicon Nitride Surface Modification and Cell Adhesion
  Abstract

Silicon microelectrode arrays (Si MEAs) have great potential in recording of neural activity; the biocompatibility of silicon nitride has gained much attention as a part of Si MEAs. In this study, we used alternating polycations, polyethyleneimine (PEI), and polyanions, gelatin, to fabricate multilayer films built up by LbL deposition on silicon nitride wafers. Then the samples surfaces were characterized by contact angle system and atomic force microscopy (AFM). The amount of proteins adsorbed on silicon nitride and modified silicon nitride were measured by a modified Coomassie brilliant blue (CBB) protein assay. Cell culture results showed that the modified silicon nitride could increase the adhesion ability of the hippocampal neurons.

  Info
Periodical
Materials Science Forum (Volumes 610-613)
Main Theme
Edited by
Zhongwei Gu, Yafang Han, Fusheng Pan, Xitao Wang, Duan Weng and Shaoxiong Zhou
Pages
1022-1025
DOI
10.4028/www.scientific.net/MSF.610-613.1022
Citation
Y. Zhao, X. Y. Lv, Z. L. Jiang, X. Li, Y. Huang, Z. G. Wang, "Silicon Nitride Surface Modification and Cell Adhesion", Materials Science Forum, Vols. 610-613, pp. 1022-1025, 2009
Online since
January 2009
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Eleana Kontonasaki, A. Sivropoulou, Lambrini Papadopoulou, P. Garefis, Konstantinos M. Paraskevopoulos, Petros Koidis
Abstract:The effect of fibronectin (FN) on human periodontal ligament fibroblasts (PDLF) attachment and proliferation on Bioglass® (PerioGlas®...
727
Authors: Huang Yan, Xiao Ying Lü, Nan Huang
Abstract:The aim of present work was to study the interaction between human plasma protein-albumin (Alb) and immunoglobulin G (IgG) and the surfaces...
893
Authors: Sorapong Janhom
Abstract:Adsorption of soybean oil Silica particles modified by cationic polymer (Polyethyleneimine, PEI) was studied. Zeta potential result shows an...
239
Authors: Arata Kaneko, Tatsuki Sugihara, Hiromichi Murakami, Iwori Takeda, Yasuhiro Tanaka, Nobuyuki Moronuki
Chapter 5: MEMS/NEMS
Abstract:The application of a neuron network to a bio/micro-sensor has potential as a drug screening device. In this study, micro-structures of...
615
Authors: Qiong Li, Hai Ning Zhang
Chapter 1: New Materials and Advanced Materials
Abstract:Fibrinogen adsorption onto surface-attached poly(methacrylic acid) monolayers and poly(methacrylic acid)/polyethyleneimine bilayers has been...
93