Paper Title:
Biocompatibility of Chitosan/Heparin Multilayer Coating on NiTi Alloy
  Abstract

Nickel Titanium alloy has been used widely in clinical iatrology for years because of its unique shape memory capability, proper elasticity and considerable biocompatibility. But as an implanted material, its possible release of Ni ions which might cause toxic effect and its improvable biocompatibility draw attentions of researchers. In this study, chitosan/heparin multilayer is coated on NiTi shape memory alloy by electrostatic self-assemble method. Field emission scanning electron microscopy (FE-SEM), contact angle test is used to show its surface character; hemolysis test, dynamic clotting time experiment and platelet binding test are utilized to investigate the blood compatibility of the materials. The results reveal that the hydrophilic character of the coated one is better than the substrate, and blood compatibility of NiTi is improved by coating treatment.

  Info
Periodical
Materials Science Forum (Volumes 610-613)
Main Theme
Edited by
Zhongwei Gu, Yafang Han, Fusheng Pan, Xitao Wang, Duan Weng and Shaoxiong Zhou
Pages
1179-1182
DOI
10.4028/www.scientific.net/MSF.610-613.1179
Citation
P. Dong, L. W. Yuan, W. C. Hao, Y. Y. Xia, G. Z. Da, T. M. Wang, "Biocompatibility of Chitosan/Heparin Multilayer Coating on NiTi Alloy", Materials Science Forum, Vols. 610-613, pp. 1179-1182, 2009
Online since
January 2009
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Price
$32.00
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