Paper Title:

Bioactivating the Surfaces of Titanium by Sol-Gel Process

Periodical Materials Science Forum (Volume 614)
Main Theme Advanced Materials Science and Technology, IFAMST 2008
Edited by Jian Lu
Pages 67-71
DOI 10.4028/
Citation Yun Cang Li et al., 2009, Materials Science Forum, 614, 67
Online since March 2009
Authors Yun Cang Li, Jian Yu Xiong, C.S. Wong, Peter D. Hodgson, Cui E Wen
Keywords Biomaterial, Hydroxyapatite Coating, Silica Coating, Sol-Gel Process, Titania Coating, Titanium (Ti)
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In the present study, titanium (Ti) samples were surface-modified by titania (TiO2), silica (SiO2) and hydroxyapatite (HA) coatings using a sol-gel process. The bioactivity of the film-coated Ti samples was investigated by cell attachment and morphology study using human osteoblast-like SaOS-2 cells. Results of the cell attachment indicated that the densities of cell attachment on the surfaces of Ti samples were significantly increased by film coatings; the density of cell attachment on HA film-coated surface was higher than those on TiO2 and SiO2 film-coated surfaces. Cell morphology study showed that the cells attached, spread and grew well on the three kinds of film-coated surfaces. It can be concluded that the three kinds of film coatings can bioactivate the surfaces of Ti samples effectively. Overall, Ti sample with HA film-coated surface exhibited the best bioactivity.