The structural Laminated Veneer Lumber(LVL) is a kind of high-performance eco-material used in the construction engineering structure. It has great significance to analyze the structural reliability for the design and manufacture of the structural LVL. In this paper, the modulus of elasticity and static bending strength of LVL manufactured by birch and poplar veneers were obtained. And the factors were also analyzed, such as wood species, veneer thickness and LVL density. The advanced first order and second moment method (AFOSM) was used to analyze the reliability of LVL. So this paper offered a method to analyze the reliability of structural LVL for designing and using reasonably.