Paper Title:
Preparation of Silicon-Containing Poly(lactic acid)-Vaterite Hybrid Membranes
  Abstract

Microfiber meshes releasing a trace amount of silicon species were prepared by electrospinning silicon-doped vaterite (SiV) and poly(lactic acid) (PLA) hybrids for application to membranes for guided bone regeneration (GBR). A trace amount of silicon-species has been reported to enhance the mineralization and bone-forming abilities of osteogenic cells. The microfiber meshes prepared by electrospinning are regarded to be a useful candidate for the GBR membrane, because they have adequate flexibility and porosity for it. In this study, hydroxyapatite (HA)-forming abilities in simulated body fluid, silicon-releasabilities, compatibility with osteoblast-like cells of the prepared microfiber meshes were examined. The meshes were completely coated with HA after soaking in simulated body fluid for 1 day. The meshes coated with HA released 0.2 -0.7 mg/L of silicon species in a cell culture medium for 7 days. The cells elongated on the microfibers of the meshes and some of them entered the mesh after 1 day-culturing. The meshes are expected to provide an excellent substrate for bone regeneration and enhance bone-forming ability of the cells.

  Info
Periodical
Materials Science Forum (Volumes 638-642)
Main Theme
Edited by
T. Chandra, N. Wanderka, W. Reimers , M. Ionescu
Pages
670-674
DOI
10.4028/www.scientific.net/MSF.638-642.670
Citation
A. Obata, T. Wakita, Y. Ota, T. Kasuga, "Preparation of Silicon-Containing Poly(lactic acid)-Vaterite Hybrid Membranes", Materials Science Forum, Vols. 638-642, pp. 670-674, 2010
Online since
January 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: G. Daculsi, Eric Aguado, Françoise Moreau, Eric Goyenvalle
Abstract:Current resorbable membranes are generally from animal origin, like collagen, and are largely used in dentistry or orthopaedic for TGR...
473
Authors: Juliana Dias, Antonio Gloria, Paulo J. Bártolo
Chapter 1: Advanced Materials and New Materials
Abstract:Non-woven scaffolds, with fiber dimensions at a nanometer scale, can mimic the physical structure of natural extracellular matrices, being...
137
Authors: Iskander M. Baybekov, Nabijon S. Sadikov, Azamat Kh. Butaev
Chapter 3: Materials Properties, Measuring Methods and Applications
Abstract:The interactions of different kind of synthetic meshes with tissuses and influence of low-intensive laser irradiation – LILI was studied in...
472
Authors: E. Gomez, J. Dias, U. D’Amora, C.A. Rodríguez, A. Gloria, P. Bártolo
Chapter 2: Biological and Medical Materials, Technologies and Engineering
Abstract:deal scaffolds for tissue engineering should mimic the complex characteristics of natural tissues and their mechanical performance. This work...
429
Authors: Matthias Schnabelrauch, Ralf Wyrwa, Henrike Rebl, Claudia Bergemann, Birgit Finke, Michael Schlosser, Uwe Walschus, Silke Lucke, Klaus Dieter Weltmann, J. Barbara Nebe
Chapter 7: Bio Materials
Abstract:Poly (L-lactide-co-D/L-lactide)-based fiber meshes resembling structural features of the native extracellular matrix have been...
1337