Paper Title:
Fabrication of Bone Substitutes by the Sponge Replica Method
  Abstract

Calcium phosphate bone substitutes are widely used for providing support for the in-growth of hard tissue in various medical applications (e.g., dental, orthopedic). Recently, research involving bone substitutes with interconnected open pore structures has focused on improving the mechanical properties of the substitutes and modifying their surfaces with proteins (e.g., collagen, bone morphogenetic protein) to induce early bone formation. In particular, it is highly desirable to develop a functional gradient-structured bone substitute that has the potential to control the bioresoption rate. A porous BCP scaffold was fabricated by the sponge replica method using a PU sponge. The sponge was dip coated three times followed by oven drying, burning out, and microwave sintering. Several approaches were used to fabricate a functional gradient scaffold. TCP was synthesized using the sol-gel process, and it infiltrated into the pore channel that formed after the burning out of the PU sponge. X-ray diffraction analysis characterized the phase identification of the BCP scaffold. Microstructures of the composites were observed using scanning electron microscopy.

  Info
Periodical
Materials Science Forum (Volumes 654-656)
Main Theme
Edited by
Jian-Feng Nie and Allan Morton
Pages
2245-2248
DOI
10.4028/www.scientific.net/MSF.654-656.2245
Citation
M. S. Kim, D. W. Jang, Y. K. Min, H. M. Yang, H. Y. Song, B. T. Lee, "Fabrication of Bone Substitutes by the Sponge Replica Method", Materials Science Forum, Vols. 654-656, pp. 2245-2248, 2010
Online since
June 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Yin Zhang, Tetsuya Kameyama, Yoshiyuki Yokogawa
Abstract:Biphasic calcium phosphate (BCP) ceramics, a mixture of hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), of varying HAp/β-TCP...
227
Authors: Min Ho Youn, Rajat Kanti Paul, Ho Yeon Song, Byong Taek Lee
Abstract:Using microwave synthesized HAp nano powder and polymethyl methacrylate (PMMA) as a pore-forming agent, the porous biphasic calcium...
49
Authors: Kristine Salma, Zilgma Irbe, Dmitrijs Jakovlevs, Natalija Borodajenko, Liga Berzina-Cimdina
Abstract:In this work three different preparation techniques of biphasic calcium phosphate (BCP) bioceramics (consisting of both hydroxyapatite (HAp)...
255
Authors: M. Ebrahimi, Naruporn Monmaturapoj, S. Suttapreyasri, P. Pripatnanont
II. Biomaterials Science
Abstract:The biphasic calcium phosphate (BCP) concept was introduced to overcome disadvantages of single phase biomaterials. In this study, we...
57
Authors: P. Saiwanich, Kamonpan Pengpat, G. Rujijanagul, U. Intatha, Sukum Eitssayeam
II. Biomaterials Science
Abstract:In this work, thepreparation and morphology of biphasic calcium phosphate (BCP) have been studied. The biphasic calcium phosphate (BCP)...
198