Paper Title:
A Novel Biodegradable Multichamber Microstructure for Implantable Drug Controlled Release
  Abstract

The research work reported in this paper design a novel biodegradable multichamber microstructure for implantable drug controlled release by introducing the approach of topology optimization. It is therefore highly desirable to overcome these restrictions that pre-defined topology of the device result in difficulty to obtain a linear or pulsed drug release profile. The designed biodegradable multichamber microstructure is fabricated using UV-LIGA microfabrication and Micro-molding technique. The simulation results show that the multichamber microstructure exhibits a preferable linear drug release profile.

  Info
Periodical
Materials Science Forum (Volumes 654-656)
Main Theme
Edited by
Jian-Feng Nie and Allan Morton
Pages
2269-2272
DOI
10.4028/www.scientific.net/MSF.654-656.2269
Citation
R. X. Yu, X. Y. Zhou, Z. Zhao, "A Novel Biodegradable Multichamber Microstructure for Implantable Drug Controlled Release", Materials Science Forum, Vols. 654-656, pp. 2269-2272, 2010
Online since
June 2010
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Price
$32.00
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