A thermodynamic model for the prediction of interfacial tension of liquid iron, inclusion and solid oxide substrate/refractory was evaluated. The combined Good’s and Young’s equations were used for high temperature liquid metal-solid oxide substrate-inclusion system to evaluate the interfacial tensions. The study predicts the liquid silicon (as model inclusion/impurity) adherence on the solid oxide substrate/refractory (MgO) in a liquid iron melt. The calculated results for interfacial tension between liquid iron-MgO values decreased from 1798 to 1026 ergs/cm2 as the temperature increases from 1823 to 1933 K, respectively. The Gibbs energy of adhesion for liquid silicon-MgO substrate was calculated shows that silicon adhesion to MgO substrate increases with increasing surface tension of liquid Fe/MgO and with decreasing temperature.