The aim of the research was to establish the relationship between stress-strain behaviour of single die Quad Flat No lead (SDQFN) and degradation by gamma irradiation. The SDQFN was exposed to Cobalt-60 with different doses from 0.5 Gy, 1.5 Gy, 5.0 Gy, 10.0 Gy and 50.0 kGy. The three-point bending technique was used to measure the flexural stress and strain of the package behaviour relations. After exposing with gamma radiation, the result showed the decreasing in the strength of the package behaviour of irradiated SDQFN when increasing the dose of gamma irradiation. The highest gamma irradiation dose used in this work produced the highest change in stress-strain behaviour of irradiated SDQFN.