Paper Title:
Effect of Morphology of Conducting Polymer on DNA Sensing
  Abstract

Electrochemical DNA sensors can be constructed by understanding basic interfacial electron transfer between solid surface-electrolyte-DNA interfaces. The kinetics of this heterogeneous process can be significantly affected by the microstructure and roughness of the electrode surface. By understanding this concept, in this paper; we compared the performance of micro electrodes containing poly(Py-co-PAA) with macro electrode containing same copolymer, showing that micro electrodes are more sensitive than the macro electrodes for biosensor applications. Sensors based on the copolymer electropolymerised on both micro and macro electrodes were evaluated across a range of oligonucleotide concentrations. The interfacial electron charge transfer resistance between the solution and electrode surface was studied using electrochemical impedance spectroscopy (EIS).

  Info
Periodical
Edited by
B. J. Ruck and T. Kemmitt
Pages
211-214
DOI
10.4028/www.scientific.net/MSF.700.211
Citation
B. Kannan, D. E. Williams, J. Travas-Sejdic, "Effect of Morphology of Conducting Polymer on DNA Sensing", Materials Science Forum, Vol. 700, pp. 211-214, 2012
Online since
September 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Li Yan Zhao, Yan Fei Tian, Jiao Yun Xia, Jing Lin He, Ling Zhang, Zhong Cao
Abstract:A novel optical biosensor with gold surface bound silver nanoparticles has been constructed for detection of oncogene of c-Myc tagged DNA...
2935
Authors: Fu Tao Hu, Yuan Zao Wu, Yu Ting Cao, Ning Gan
Chapter 2: Inorganic Nonmetallic Materials
Abstract:A novel and sensitive electrochemical enzyme-linked immunosorbent assay (ELISA) system of Hydroquinones (HQ)- peroxide hydantoin (CP)...
200
Authors: Li Bo Nie, Hao Chang, Zhu Chen, Quan Guo He
Chapter 19: Biological Information Technology
Abstract:As the substrates of biosensor or biomicroarray, silicon, silica and gold matrixes are usually used as the surfaces of bio-recognition. In...
2991
Authors: Wen Pin Hu, Li Ya Huang, Wen Yih Chen
Chapter 1: Materials Engineering and Processing Technologies of Materials
Abstract:A stable and versatile biosensor surface is a desirable feature for any sensor, and the DNA-directed immobilization (DDI) of protein-DNA...
398
Authors: Ting Ting Gu, Hong Qi Xia, Jian Li Wang, Da Wei Yang, Yang Zhao, Mo Han Liu, Zhi Gang Fang
Abstract:Horseradish peroxidase (HRP) and toluidine blue (TB) were incorporated in polyion complex membrane composed of double stranded DNA(dsDNA) and...
84