The present study deals with deformation behaviour of textured Zircaloy 2 with two dominant orientations: basal and non-basal. During initial stages (20%), two distinct class of grains were observed – non-deforming/non-fragmenting grains and deforming/fragmenting grains. The so-called non- deforming/non-fragmenting grains remain equiaxed even after 50% of deformation. They also have insignificant in-grain misorientation developments and have more residual stresses. Dislocation dynamics simulation showed that the dislocation interactions/mobility is insignificant in basal orientations at room temperature deformations.