Paper Title:
Hybrid HAp-Maleic Anhydride Copolymer Nanocomposites Obtained by In Situ Functionalisation
  Abstract

The aim of the work is to establish if maleic anhydride copolymer acts as a grain growth modulator and/or as a biocompatible functionalisation agent for hydroxyapatite. Experimental work was developed in three directions: nanocomposites synthesis, nanocomposites characterization and citotoxicity tests on nanocomposites. Maleic anhydride copolymer – HAp nanocomposites were prepared by in situ functionalisation in hydrothermal conditions and were characterized by chemical quantitative analysis, XRD, FT-IR, SEM, specific surface area and picnometric densities. Chemical bonding between the copolymer carboxyl groups and calcium ions of HAp induced a peak of 1577 cm-1 on the FT-IR analysis. Following the evolution of this characteristic peak with the hydrothermal synthesis conditions (different temperatures and pressures) and corroborates the results with XRD and SEM analysis it was pointed out the copolymer grain growth modulator behaviour. Citotoxicity studies in vitro on mice fibroblast cultures were performed. The results proved the biocompatibility of new hybrid –polymer nanocomposites.

  Info
Periodical
Solid State Phenomena (Volume 106)
Edited by
Radu Robert Piticescu, Witold Lojkowski and John R. Blizzard
Pages
47-56
DOI
10.4028/www.scientific.net/SSP.106.47
Citation
R. M. Piticescu, G. C. Chitanu, M. Albulescu, M. Giurginca, M. L. Popescu, W. Łojkowski, "Hybrid HAp-Maleic Anhydride Copolymer Nanocomposites Obtained by In Situ Functionalisation", Solid State Phenomena, Vol. 106, pp. 47-56, 2005
Online since
September 2005
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Luis M. Rodríguez-Lorenzo, Blanca Vázquez, Julio San Román
Abstract:Hydroxyapatite has been frequently described as an osteoconductive but not osteoinductive material based on failure to observe bone...
357
Authors: Caihong You, Toshiki Miyazaki, Eiichi Ishida, Masahiro Ashizuka, Chikara Ohtsuki, Masao Tanihara
Abstract:Organic polymers with ability of apatite formation in body environment are expected as novel bone substitutes having not only bone-bonding...
469
Authors: Frank A. Müller, Kristina Lessnau, Lenka Müller, Marcus W. Rauch, Cordt Zollfrank, Peter Greil
Abstract:A composite material consisting of cellulose and HAp was prepared using coagulation of a native cellulose suspension. Composite tapes with a...
1173
Authors: Isabel B. Leonor, Hyun Min Kim, Francisco Balas, Masakazu Kawashita, Rui L. Reis, Tadashi Kokubo, Takashi Nakamura
Abstract:Sulfonic groups (-SO3H) were covalently attached on different polymeric surfaces enabling them to induce apatite nucleation, for developing...
966
Authors: Roxana M. Piticescu, Gabrielle Charlotte Chitanu, Aurelia Meghea, Maria Giurginca, Gabriela Negroiu, Laura Madalina Popescu
Abstract:A comparative study of the in situ interactions between different maleic anhydride based copolymers and calcium phosphates is presented in...
387